Systemic Inflammation - HeaToxin

Heatoxin

50 x 500 mg capsules  

Actions

• Immunosuppressive

• Anti-inflammatory

• Protects against autoimmunity

Indications

• Autoimmune diseases

• Rheumatoid Arthritis

• Immune suppression 

• Pernicious anaemia

• Systemic Lupus Erythematosus (SLE)

• Sjogren's syndrome 

Ingredients

Artemisia apiacea 
(contains: 6:1 extract standardised artemisinin)

Cordyceps sinesis (Dong Chong Xia Cao)

Paeonia suffruticosa (Mu Dan Pi)

Paeoniae obovata (Chi Shao)

Oldenlandiae (Bai Hua She She Cao)

Folium Isatis (Da Qing Ye)

Erythrina variegata (Hai Tong Pi)

Grape Seed extract (Pycnogenol)

Other Ingredients: Vegetable cellulose (hypromellose); Vegetable Stearic Acid; Microcrystalline Cellulose and Vegetable Magnesium Stearate.

Does not contain: Wheat, gluten, soy, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts   

Caution: May cause loose stools. Long term administration (greater than 1 month) should be monitored and include liver enzymes and haemoglobin testing. Combining with antioxidants or iron may theoretically decrease effectiveness. Detoxification reactions may be experienced by some individuals. In rare cases may cause idiosyncratic liver dysfunction. 

Warning: Do not use if pregnant or breast feeding 

Suggested Use: 2 to 6 capsules as needed. 2 capsules is considered a maintenance dose, twice daily morning and evening. Sensitive individuals may want to take with food. 

Key Ingredients

Artemisia apiacea (contains standardised artemisinin) (Chinese Wormwood) (Qing Hao)

Artemisinin attribute immunomodulatory distensions. For instance, it demonstrates predominant immunosuppressive traits toward different immune components by particularly regulating the cellular proliferation and cytokine release, which indicates that they possess some additional mechanisms and features demanding deliberate attentions. This article reviews immunomodulatory effects of artemisinin's on different immune cells including neutrophils, macrophages, splenocytes, T and B cells in conjunction with their therapeutic prospective with regard to inflammation, autoimmunity and delayed-type hypersensitivity.1 ,2

References

1:  Shakir L, Hussain M, Javeed A et al. Artemisinins and immune system. European Journal of Pharmacology. Volume 668, Issues 1–2, 1 October 2011, Pages 6–14

2. Wang Y, Huang Z, Wang L, et al. The anti-malarial artemisinin inhibits pro-inflammatory cytokines via the NF-kB canonical signaling pathway in PMA-induced THP-1 monocytes. Int J Mol Med. 2011 Feb;27(2):233-41. doi: 10.3892/ijmm.2010.580.

3 Lu L. [Study on effect of Cordyceps sinensis and artemisinin in preventing recurrence of lupus nephritis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Mar;22(3):169-71. Chinese. PubMed PMID: 12585097.

Cordyceps sinensis (Dong Chong xia cao)

References

1. WANG Feng, WANG Ling, ZHANG Cai-Jun, LI Bing-Xue. Kun Ming Yi Xue Yuan Xue Bao. 2009; 30(2): 36-39.

2. Lu L. [Study on effect of Cordyceps sinensis and artemisinin in preventing recurrence of lupus nephritis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Mar;22(3):169-71. Chinese. PubMed PMID: 12585097.

Paeonia suffruticosa (Tree peony) (Mu Dan Pi)

References

1. Wang Xianling, Li Lianzhen, Jing Yun, Wu Shuming. He Nan Zhong Yi. 2005; 25(12): 26-28.

2. WU Haijun, XU Jihui, LI Yueling, LIU Heli, YANG Yumei. Bao Tou Yi Xue Yuan Xue Bao. 2008; 24(3): 238-239.

Paeoniae obovata (Chinese Peony) (Chi Shao)

References

1. Lue Jinshun Wang Xinfeng Bo Yingying. Lin Ye Ke Xue. 2009; 45(1): 161-166.