CNS Factor ( Neuro)

NeuroFactor is a clinically formulated blend of Euphoria longana, Houttuynia cordata, Dioscorea japonica with Schisandra chinensis (Schisandrin B). The NeuroFactor combination of Euphoria longana, Houttuynia cordata and Dioscorea japonica has been researched to exert antidepressant effects and increase Brain-derived neurotrophic factor (BDNF) levels in the brain. Schisandra a well- known adaptogen and cognitive aid, has been included for its antioxidant-neuroprotective, mood balancing and anti-inflammatory effects. 

Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor widely expressed in the CNS. It has a neuroprotective effect playing an important role in neuronal survival. In the brain, BDNF is involved in plasticity, formation of new synapses, dendritic branching, and modulation of excitatory and inhibitory neurotransmitter profiles. BDNF is active at all stages of development and is essential for learning and memory. Low levels of serum BDNF have been associated with depression implying an inverse relationship between serum BDNF levels and the severity of depression. Decreased levels of BDNF are also associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, multiple sclerosis and Huntington's disease.1-2

Actions 
Anti-depressant
Anxiolytic
Adaptogen
Reduces effects of stress
Improves memory, cognition and attention
Regulates heathy sleep cycle
Increases Brain-derived neurotrophic Factors (BDNF)
Regulates stress hormone production
Reduces serum levels of cortistatin, adrenocorticotropic hormone (ACTH), and corticotropin-releasing factor (CRF)
Upregulates GABAA receptors
Reduces glutamic acid levels
Increases serotonin 

Indications 
Depression (Treatment-Resistant Depression (TRD)) 
Anxiety
Chronic stress
Stress related memory impairment
Cognitive impairment
Neurodegenerative conditions

Dose 

1-2 capsule BID 

Cautions 

Caution in pregnancy.